Newly Identified CYP2C93 Is a Functional Enzyme in Rhesus Monkey, but Not in Cynomolgus Monkey
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منابع مشابه
Newly Identified CYP2C93 Is a Functional Enzyme in Rhesus Monkey, but Not in Cynomolgus Monkey
Cynomolgus monkey and rhesus monkey are used in drug metabolism studies due to their evolutionary closeness and physiological resemblance to human. In cynomolgus monkey, we previously identified cytochrome P450 (P450 or CYP) 2C76 that does not have a human ortholog and is partly responsible for species differences in drug metabolism between cynomolgus monkey and human. In this study, we report ...
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Myocardial necrosis can be result from a number of causes including nutritional deficiencies, chemical and plant toxins, ischemia and metabolic disorder. The outcome of myocardial necrosis varies depending on the extent of the damage (Donald 2001, Jubb 1993, Radostits 1994, Vanvaleet 1986). Myocardial infarction without demonstrable of atherosclerosis were reported in a rhesus macaque (Gonder 1...
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متن کاملCynomolgus and Rhesus Monkey Visual Figments
Microspectrophotometric measurements were performedon 217 photoreceptors from cynom*us, Macacafascicularis, and rhesus, M. mulatto, monkeys. The distributions of cell types, for rods and blue, green, and red cones were : 52, 12, 47, and 44, respectively, for the cynomolgus, and 22, 4, 13, and 13 for the rhesus. Visual cells were obtairled fresh (unfixed), mounted in various media (some containi...
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myocardial necrosis can be result from a number of causes including nutritional deficiencies, chemical and plant toxins, ischemia and metabolic disorder. the outcome of myocardial necrosis varies depending on the extent of the damage (donald 2001, jubb 1993, radostits 1994, vanvaleet 1986). myocardial infarction without demonstrable of atherosclerosis were reported in a rhesus macaque (gonder 1...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2011
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0016923